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A pancreatic cancer diagnosis can cause a range of emotions including fear, anxiety and uncertainty about the future. Because symptoms are often subtle in the early stages, pancreatic cancer is commonly diagnosed at a later stage, making early detection and timely intervention critical.

Although pancreatic cancer can be particularly difficult to treat, recent advances in medical technology have reshaped the treatment for pancreatic cancer and include innovative surgical procedures. 

Surgery remains the gold standard treatment for treating pancreatic cancer in combination with chemotherapy, radiation therapy and immunotherapy, when necessary, and diagnosis at an early stage remains critical for the best options for a cure.

Understanding Pancreatic Cancer

The pancreas is a small organ (about six inches in length) located in the center of the abdomen, close to the stomach, intestines, and other organs. It is situated behind the stomach and in front of the spine. The pancreas produces digestive enzymes and hormones to digest the food we eat.

Pancreatic cancer occurs when cancer cells form and grow within the pancreas. The most common form of pancreatic cancer is pancreatic ductal adenocarcinoma, which is caused when the cells in the inner lining of the pancreatic duct transform into cancer cells.

Advanced Treatment Options

Diagnosis of pancreatic cancer in early stages is critical for best treatment options transforming into good outcomes, although they don’t typically present with symptoms. Once the diagnosis is made, timely intervention with a multidisciplinary team consisting of pancreatic surgeons, oncologists, gastroenterologists, radiologists, pathologists and other specialists is critical. 

If the cancer is diagnosed early enough to be removed by surgery, this treatment is often considered the best and first chance for a cure. Surgery followed by chemotherapy with immunotherapy and sometimes radiation definitely augments cancer outcomes. The best chance for cure is a multimodality approach with all treatment options.

The Whipple Procedure

When cancerous tumors are detected within the head of the pancreas, the standard of care is to surgically remove the tumors and cancerous tissue before they spread. This procedure is known as the Whipple Procedure, also referred to as a pancreaticoduodenectomy.

The goal of a Whipple procedure is to remove the cancer and prevent it from growing and spreading to other organs. For early stage pancreatic cancer, this procedure is the treatment that can lead to long-term survival.

The Whipple procedure is an extremely complex abdominal surgery that is performed to treat tumors of the head of the pancreas, lower part of the bile duct and around the ampulla. It involves removing the head of the pancreas, the duodenum (the first part of the small intestine), the gallbladder, part of the bile duct, sometimes a portion of the stomach and the surrounding lymph nodes. The remaining part of the stomach, bile duct and pancreas are then reconnected to the digestive tract to restore the flow of ingested food, digestive enzymes and bile.

In some cases, a pylorus-sparing Whipple (a modified Whipple procedure) may be performed. In this case, the entire stomach is preserved including the pylorus (a valve between the stomach and the duodenum).

Candidates for the Whipple Procedure

The Whipple procedure is an option for patients whose cancer is confined to the pancreas or the small area adjacent to it. Patients should be in good health without other underlying conditions, and healthy enough to reasonably anticipate that they will fully recover.

The Whipple procedure is generally not considered for patients whose cancer has spread to other organs or parts of the body. Since it is a complex surgery, it is usually not recommended for patients that are frail or not strong enough to make a full recovery.

A multidisciplinary team of cancer specialists and oncologists will perform a comprehensive evaluation of a patient’s health and stage of cancer, including imaging tests and biopsies, to determine if the Whipple procedure is the right course of treatment.

Robotic-Assisted Whipple Procedure

Until recently, the Whipple Procedure was traditionally performed by conventional open surgery, through a large abdominal incision to access the pancreas. While this approach remains the most commonly performed technique, the advanced, robotic minimally invasive technique offers additional benefits.

Dr. Anantha

“A robotic-assisted Whipple procedure is still a highly complex surgery. But this innovative technique allows us to perform the same surgery with precision and quality, without making a large incision. This enhances recovery, making the hospital stay shorter with reduced post-operative pain.”

The latest, innovative advancement in pancreatic surgery has been the use of robotic-assisted surgery. The robotic-assisted Whipple procedure uses advanced robotic technology to give the surgeon enhanced 3D vision, precision and control using more minimally invasive techniques to perform the surgery.

With this procedure, the surgeon operates through several small incisions, using robotic arms equipped with special wristed instruments and a tiny high definition 3D camera. The robotic instruments move precisely along with the surgeon’s hands and the camera provides a complete 3D view of the operative field. The robotic instruments remain in the surgeon’s control at all times, reassuring patient safety and precision.

Medical studies have shown that robotic Whipple procedures offer outcomes that are equal to or better than open surgery, not compromising surgical precision and quality – with fewer complications and shorter hospital stays.

Benefits of the Robotic-Assisted Whipple Procedure

Robotic surgery is safer and less invasive than open surgery, and most patients usually experience fewer complications when performed at high-volume centers with experienced surgeons. The benefits of robotic-assisted Whipple surgery can include:

  • Less post-operative pain
  • Lower risk of infection
  • Less blood loss
  • Shorter hospital stay
  • Quicker recovery period

Risks of the Whipple Procedure

The Whipple procedure is a complex surgery, regardless of the surgical technique. As with any surgical procedure, there are risks and possible complications, which may include:

  • Bleeding - Blood loss may occur during or after the procedure
  • Infection – At the incision site or within the abdomen
  • Slow emptying of the stomach, which may make it temporarily difficult to eat or to keep food down
  • Anastomotic leak- Leakage from where the surgical connection was made to the pancreas, bile duct, or stomach
  • Nutritional deficiencies – Difficulty digesting food and absorbing nutrients may cause weight loss and malnutrition
  • Diabetes – Removing part of the pancreas can affect insulin production, potentially leading to diabetes

Whipple Procedure Recovery

After undergoing a Whipple procedure, most patients will remain in the hospital for a period of time so they can be closely monitored. During the first few days of recovery, they will be restricted from eating solid food. After they are released from the hospital, patients will receive specific post-operative instructions about the reintroduction of solid food and physical activity.

Most people return to their usual activities approximately four to six weeks after surgery, however, this time frame may vary for each patient and how difficult the surgery was. During the first few months of recovery, patients may feel tired and easily fatigued, but will see gradual improvements in their strength and energy levels over time.

Long-Term Outcome after a Whipple Procedure

The Whipple procedure is an effective surgery for pancreatic cancer, primarily when the tumor is located in the head of the pancreas and has not spread extensively. Survival rates depend on the type of cancer, the stage and other factors.

The patient’s recovery will be monitored and additional tests will be performed to determine if all the cancer was successfully removed. Depending on the results, additional treatments like chemotherapy or immunotherapy will be recommended to complete your cancer treatment plan.

The robotic technique offers the benefits of less postoperative pain, quicker recovery and less complications with similar oncologic outcomes as the traditional Whipple procedure.

Learn more about cancer treatments and advanced care for pancreatic cancer at Catholic Health.

Find Care at Catholic Health

Find a Catholic Health doctor near you. Or call 866-MY-LI-DOC (866-695-4362).

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