The prostate is part of the male reproductive system. It is a small gland that is located just below the bladder and in front of the rectum. This tiny gland secretes seminal fluid that mixes with sperm, keeping it healthy for conception. The prostate is about the size of a walnut and it tends to grow as a man ages.
Prostate cancer develops when abnormal cells form and grow in the prostate gland. The cancer usually grows slowly and most tumors are diagnosed before the cancer has spread beyond the prostate. The good news is that prostate cancer is highly treatable at this stage.
According to the American Cancer Society, other than skin cancer, prostate cancer is the most common cancer among men in the United States. About one in eight men will be diagnosed with prostate cancer during their lifetime. The risk for prostate cancer can vary, based on age, race/ethnicity and other factors.
Symptoms
In the early stages, prostate cancer often has no symptoms. As it progresses, symptoms may develop including:
- Frequent urination, especially during the night
- Difficulty starting or stopping the flow of urine
- Inability to urinate
- Pain or burning during urination
- Blood in the urine (hematuria)
- Painful ejaculation
- Weak urine flow
- Pain in the lower back, hips, or upper thighs
While some of these symptoms may mimic those of prostate cancer, they are often caused by less serious, benign conditions including benign prostatic hyperplasia (BPH), urinary tract infections, or prostatitis. If you are experiencing any of these symptoms, consult with your primary care doctor or urologist for a thorough evaluation.
Causes and Risk Factors
The exact cause of prostate cancer is unknown; however, certain factors may increase a man's risk for the disease. The most common risk factors include:
- Age: The risk increases as men get older and men are more commonly diagnosed after the age of 50. About 60% of prostate cancers occur in men older than 65.
- Race/Ethnicity: There is a higher risk for African American men and men of Caribbean descent. The reasons for these racial and ethnic differences are not clear.
- Family History: Men are more likely to develop prostate cancer if they have a family member with the disease. Having a father or brother with prostate cancer more than doubles a man’s risk of developing this disease.
Other potential risk factors may include:
- Smoking
- Prostatitis (Inflammation of the prostate gland)
- Obesity - Having a BMI greater than 30
- Sexually transmitted infections
- Chemical Exposures - There is some evidence that firefighters can be exposed to chemicals that may increase their risk of prostate cancer. Other studies have suggested a link between exposure to arsenic and a higher risk of prostate cancer.
Screening for Prostate Cancer
Screening tests can indicate whether you have signs of prostate cancer that require more testing.
The general guidelines for prostate cancer screenings recommend starting at the age of 50. However, men with a family history or other risk factors may benefit from screening as early as age 40. Speak with your health care provider to determine when you should be screened for prostate cancer. Learn more about prostate cancer screenings and PSA testing.